Well... at the risk of coming as a sanctonimous piece of fudge
I don't think explotation is an anime only thing, there's plethora of adult american shows that rely on being as gross and shocking as possible not only with violence and gore, but also sex, in that regard Family Guy is not an outlier (and even then, its humor managed to be edgy in earlier seasons without being as gross as it bacame later on, so I don't think it being a joke or played for laughs makes it any more valid to rely on explotation of any kind if that in itself is questionable). Think also comic books and films, where they can also include some pretty nasty stuff just for the sake of it, like any slasher series where the drawing point is to see how messily and gorily the murderer will kill everyone (who a lot of the times people randomly having sex and partying). And even for kids in the 90s and 2000s there were plenty of stuff that relied entirely on toilet humor. And "erotic" content was also quite common in europe until regulations came in.
What I am trying to say is that, disgusting crap has always been a thing and has been around everywhere. I think anime gets a worse rap because it's one of the more mainstream media around (and, let's not kid ourselves, exploitative, fanservice heavy works do get a lot of attention from audiences), cultural differences being at play over what can be portrayed in media between countries, and sex in general being a very taboo subject (I mean, when something of the sort slips into mainstream western media, expect a massive meltdown in social sites).
Now, I do agree that anime has a lot of stuff that ranges from questionable to ourtight wtf worthy. And it's fully understandable if it creeps or grosses you out to the point you drop the show. But I think the point that's being made, is that regardless of how messed up a work is, it shouldn't be compared to the abuse and explotation of real people, where actual individuals are hurt and traumatized.