so since Haki isn't negating GJ or Amenotejikara
Sasuke's wincons are:
- Beating Zoro early on due to AP gap
- GJ (Basic or at worse case scenario Izanami)
- BFR via Amenotejikara
- Soul Rip
- Sealing via CT
- Death Manip via KOH (albeit Adult Sauce probably won't try this)
- Outlasting En-O Zoro if it gets to that point.
Zoro's wincons are:
- Beating Sasuke with AP in stronger forms (via Adv Hao and En-O Santoryu)
- LS (Not that Zoro usually chooses to do that over using his sword styles)
Sasuke's wincons require glances to get off for the most part while Zoro's requires his strongest form to oneshot Sasuke before overtaxing his maximum Haki output via Enma makes him drop.
Sasuke has shown he can contend and evade people much stronger than him and Zoro via Kaguya, Jigen, and Isshiki through use of illusions, teleportation, substitution, or just good evasion via sharingan.
Both do have valid forms of knowing what the other will do before they even try it.t.
But if Sasuke does take any kind of incapacitating damage he can use Izanagi as a last resort to negate the damage and kill Zoro with the entire minute of being able to ignore injury or death.
Sasuke should handily take this.