The microbursts should be able to. A weaker witch than Sanura was able to blow open a hole in a wall of water made by 40 water witches with just one. A traveling storm of them around Assefa's body should help, seeing as how Peter can't land physical attacks on him without first getting around the microbursts. Though, to be fair, this was before either of them were 8-A. But I suppose it's just to show what the microbursts are capable of. They hit with rather explosive force. A hard impact, which I believe to be suitable for dispersing the webs.
To be fair, I didn't realize he had web grenades. Though I don't think that's too much different from blowing a hole in a wall of water fueled by the magic of an entire witch coven. I don't think the webs will be able to get through all that easily, if at all. And even if they do get through, I think they'd be weakened enough that Assefa himself can take care of the remainder. The webs aren't magical so they're not going to dispel of the enchantment on Assefa. It'll stay up, which will still make close ranged combat difficult for Spidey. Though, to be fair, Assefa will also find it incredibly difficult to land a hit on Spiderman. His spider sense is better than his supernaturally enhanced senses.
And it seems the webs have resistance to fire. I completely forgot about that bit during Infinity War. (And the piece during homecoming as I didn't go see that). That's a well made point. I do doubt that those flames were 8-A. But showing heat resistance is all that's really necessary I believe.
I do think that Sanura's necklace would rather severely cripple Peter, and make it difficult for him to make a comeback, as the necklace heals wounds and restores stamina. And it potentially bypasses durability to an extent. Most of the supernatural creatures they fight have increased durability due to either their scales, toughed/hardened skin, a shell, or some other aspect of their physiology. The flames didn't seem to care about that, and made the victory against a creature that had previously broken Assefa's back, in Mngwa form, quite simple. Though the creatures was also damaged from the battle with Assefa already. And, once again, this was in their 9-B forms, but the same thing should apply to their 8-A versions.
I still believe it's closer to inconclusive. Assefa's primary win condition is crippling Spidey with Sanura's necklace, and going to town once he's crippled. But I think Spidey will be hard pressed to get through the microbursts. Especially considering that they repelled multiple creatures of Assefa's level at once.
And thank you for replying.