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Akame takes this, I think. Ban is likely to sit there and expect his Regenerationn to see him through and wouldn't really bother to use Physical Hunt or Fox Hunt at first. Meanwhile, Akame needs just a scratch to win and with Ban's mentality, I see that happening.
I don't think so but can Regenerationn help against poison? I saw a thread where it was said that poison would work against someone with Mid-High Regenerationn.
In the original chapters of the manga, Murasame's poison is shown to stop the heart to kill the target in moments. Ban has been put through every kind of execution the Holy Knights could come up with, which would naturally include any kind of neurotoxin.