Wew boy, this may be a dousey. So if the KHR revision page is anything to go by, Tsuna is roughly baseline or around a few times stronger going off scaling and multipliers. For Samus, AP doesn't really mean much when she has numerous ways to negate durability right off the bat. And for this tier, she can attack the soul and freeze you in ice. Tsuna's hyper intuition may be screwed a bit here since she has a suit, and going off the robot fight he had in the future arc, his precog isn't that great against non-organic things. Even if it won't be affected by that much, Samus' precog can easily counter his hyper intuition. Unfortunately for Tsuna, Samus doesn't have any fire related weapons, so his absorption technique won't work here. His best move I think would have to be zero point, buuuuuut if things go the way they seem, samus might resist ice manipulation, or even better, absolute zero if Metroid fusion is anything to go by, though the latter part I need to double check.
As for the whole "what does she do in character, well she starts by shooting the ever living crap out of her foes, and her beams stack on top of each other, so it's gonna hurt really badly off tsuna gets hit. Overall, I think Samus might have the edge here, though I do have a feeling that this match might be a stomp if Samus does resist ice, which makes Tsuna all the more screwed as I don't recall him ever using petrifying at his opponents, especially right off the bat.
