do
I am giving Toga as a example. What if someone is born with a quirk that makes them want to murder instead of drink blood. Oh Wait Moonfish already exists as an example.
There is a difference between Optimistic and stupid. There is nothing Edgy about quoting scientific data.. The fact that you call me a edgy doomer, just goes to show how many assumptions you make in your answer. Neither do you know anything about me, or what you are talking about.
People with power more often that not go towards evil. It's a well know psychological trait. Anby tyrant in history went crazy with power after they realized how much power they had, take Nero for example.
"Although both biological and environmental factors play a role in the development of psychopathy and sociopathy, it is generally agreed that
psychopathy is chiefly a genetic or inherited condition, notably related to the underdevelopment of parts of the brain responsible for emotional regulation and impulse control."
_ Encyclopedia Britannica
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"Several authors have argued for a genetic or hereditary pathway toward psychopathy (Auty, Farrington, & Coid,
2015; Blair,
2003,
2006; Viding et al.,
2005). The notion is that psychopathic individuals inherit a genetic makeup that manifests in altered brain functioning and physiological reactivity, and along with some environmental triggers or influences, shapes their behavior in childhood (Blair,
2003,
2006; Viding et al.,
2005). For instance, Viding et al. (
2005) reported finding strong evidence of heredity and no evidence of shared environmental influences in their study of 7-year-old twins with antisocial behavior and CU traits. Similarly, Auty et al. (
2015) found strong evidence of transmission of psychopathy from fathers to their children, though this was mediated by environmental factors. Given the strength of genetic influence reported in these and similar findings, examining the evidence for specific genetic factors is important.
5.1. MAO-A
The strongest cumulative evidence base for a genetic pathway toward psychopathy is associated with the low-expression variant of the
Monoamine Oxidase-A (
MAO-A) gene, which encodes an enzyme that degrades mono-amine neurotransmitters – that is, dopamine, norepinephrine, and serotonin (Caspi et al.,
2002; Cicchetti, Rogosch, & Thibodeau,
2012). The low-expression variant of the
MAO-A gene is linked to the X chromosome. Possessing only a single X chromosome, males are more likely to be influenced by a low-expression variant (Hunter,
2010).
In all eight studies investigating
MAO-A polymorphisms (Beaver et al.,
2013; Caspi et al.,
2002; Fowler et al.,
2009; Kolla et al.,
2015; Longato-Stadler et al.,
2002; Sadeh et al.,
2013; Williams et al.,
2009; Young et al.,
2006), statistically significant correlations were identified between the short allele and psychopathic and/or antisocial traits. The use of differing measures of psychopathy and antisocial behavior, along with inadequate delineation of participants’ histories of criminality and delinquency from the psychopathy construct, posed a significant limitation for many studies. Several authors found associations between subjects’ criminality and a lower-expression variant of the
MAO-A gene (Beaver et al.,
2013; Kolla et al.,
2015; Sadeh et al.,
2013), or specifically investigated APD diagnosis (Longato-Stadler et al.,
2002; Young et al.,
2006), which placed significantly more weight on rule-breaking behavior (Hare,
1996). Focusing specifically on core psychopathic traits, only two studies (Kolla et al.,
2015; Williams et al.,
2009) identified significant differences between carriers of lower- and higher-expression
MAO-A variants (i.e., increased psychopathic traits in short allele carriers). Fowler et al. (
2009) found lower-expression
MAO-A variants to be significantly related to emotional dysfunction scores in youth diagnosed with attention deficit hyperactivity disorder (ADHD), but the cumulative effect size for the same relation with total psychopathy-related scores was medium-sized (
f2 = 0.16).
In 2002, Caspi et al. observed an interaction between childhood adversity and the MAO-A risk allele, demonstrating that for those who carried this allele, adversity was positively related with psychopathy. Building on findings from Caspi et al. (
2002), several subsequent MAO-A studies (Sadeh et al.,
2013; Williams et al.,
2009; Young et al.,
2006) included measures of childhood adversity or maltreatment. However, whereas some studies found associations between maltreatment, adversity, and rule-breaking behavior (Sadeh et al.,
2013; Young et al.,
2006) or between the risk allele and antisocial behavior in participants who experienced severe family adversity (Fowler et al.,
2009), others did not (Williams et al.,
2009). Notably, these studies varied not only in their measures of psychopathic traits but also in their measurement of adversity and maltreatment. For instance, Williams et al.’s (
2009) analysis used only a dichotomous adversity score, comparing participants who experienced more than three adverse events to those who experienced three or fewer. Nonetheless, the interaction between MAO-A and maltreatment observed by Caspi et al. (
2002) was not replicated in these subsequent studies.
5.2. 5-HTT
Based on observations of reduced serotonin in aggressive and impulsive individuals (Ferguson & Beaver,
2009; Goodman & New,
2000; Lesch & Merschdorf,
2000), multiple studies have sought to associate 5-HTT with psychopathy. Findings in the seven studies that examined this relationship (Fowler et al.,
2009; Garcia et al.,
2010; Hallikainen et al.,
1999; Sadeh et al.,
2010, experiments 1 and 2; Sadeh et al.,
2013; Van de Giessen et al.,
2014) were inconsistent. Sadeh et al. (
2013), for instance, found that PCL:SV Factor 2 scores were significantly related to carrying the long allele of 5-HTT and to Childhood Trauma Questionnaire scores, though no interaction was identified. Similarly, in Sadeh et al. (
2010, study II), CU traits increased in long/long allele carriers, but only as socioeconomic resources decreased. In contrast, aggression, impulsivity, and antisocial behavior was found to be related to carrying the short allele of 5-HTT (Garcia et al.,
2010; Sadeh et al.,
2010, study I). No relation between aggression and 5-HTT availability was identified in Van de Giessen et al. (
2014), but the authors observed a positive relation with callousness traits.
5.3. Dopamine receptor genes
Because of their role in the pleasure/reward system in humans, dopaminergic system genes have been a source of considerable research relating to violence, aggression, and antisocial behavior (Ferguson & Beaver,
2009; Ferguson,
2010). Nonetheless, only three of the studies investigated dopaminergic gene systems (Hoenicka et al.,
2007; Ponce et al.,
2008; Wu & Barnes,
2013). An additional study (Fowler et al.,
2009) investigated the
COMT gene, which regulates the production of the dopamine degrading enzyme, and is therefore discussed here as well.
All four studies reported relatively small impact of dopaminergic system genes. For instance, Fowler et al. (
2009) reported the high-activity
COMT genotype was statistically associated with significantly higher emotional dysfunction scores, with a small effect size (
f2 = 0.08), and without significant impact on total psychopathy scores. Wu and Barnes (
2013) found that only DRD4 (and not DAT1 or DRD2) was significantly related to psychopathic personality traits. Yet carrying two DRD4 risk alleles (as compared to zero) increased participants’ mean psychopathy scores by only two points (from 55.97 to 57.99, on a scale of 23–115). Hoenicka et al. (
2007) and Ponce et al. (
2008) found
DRD2 gene polymorphisms to be associated with higher scores on the International Personality Disorder Examination (IPDE). Hoenicka et al. (
2007) reported these genetic markers (when combined) may be responsible for 11.4% of the variance in psychopathy scores."
- National Institutes of Health (NIH) (.gov)
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And at the end of it, this is a security question, not a philosophical one. It should be approached by logic. The question is, was it worth it to sacrifice OFA and not achieve jackshit. Leaving the world with far less protection.
If a small country like Japan can have this strong villains, any high population country would have insane rate of strong quirks because of sheer numbers.
Yes Deku can't protect the world forever. But neither can any society level changes. Societies collapse and people change. Deku could have kept the world world safe for over 80 years. That's longer that how long has it been since WW2.
Peace will break. OFA would have just given world more time.