Holy element and spirit particles are completely separate. Holy element and by extension Holy Magic purifies magicules. Spirit Particles do not. And that means any Holy Magic that doesn't use holy elements (yep that's a thing) but simply spirit particles won't have that effect.
That's interesting, I think you might be correct. But I've also read that spirit particles purify magicules, or maybe I'm just misremembering.
What is consistently undeniable fact though is that the Holy Magic that purifies magicules aren't really harmful to humans (unless intended to be use that way). Meanwhile Spirit Particles, like Disintegration, would actually erase everything, monster or not, magicule or not.
I don't think Demonic element is magicules, especially since even humans have magicules. But just an unquantifiable quality innately possessed by monsters. You could say its what truly distinguishes what a monster is.
According to Tensura Fan, the demonic element refers to magicule, and only monsters possess magicule as humans use mana and the holy element counters monsters.
This is one of the great inconsistencies I'm talking about, because FUSE might have intended to make that distinction at some point in the story, but may have gotten lazy, which is why most of the time, literally everyone including humans have magicules.
There are rare times where humans are described to have mana instead of magicules, but the monsters are described to use mana too, multiple times each volume.
Then there are times like when Fritz ate the Black Magic Rice and his Resistance to Magicules "converted the mana into energy", and how Saint Yuuki has the energy that, if converted into magicules, puts him on par with Ruminas and Leon.
It's true that monsters are innately possessing magicules though.
I updated a lot of Beretta's profile. I think the only thing it needs is if Beretta had any additional abilities in his Chaos Doll form. Also if there are any scans for them, as well as his resistances. It would be nice if there's a scan of his stats like the other characters too, if there are any.
I'll make a CRT about him and some other characters soon.