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Yes, this is a legitimate question. In "Attack of the 50 Foot Sister", Doofenshmirtz' invention gets activated with Phineas and Ferb's growth elixir in the device. The device then accidentally gets set to affect the entire universe of Phineas and Ferb. This causes everything and everyone in the universe to grow in size by the end of the episode. As far as I know, this has never been reversed. So would Phineas and Ferb characters have large size?