Okay. Wanna talk about Mind-Destruction, then let's talk about Slaanesh. Namely, Slaanesh's Palace.
Firstly, it takes place in the Warp, but on a lower-domain of the Warp specifically designed to affect mortals, rather than a Higher-Dimensional location like Tzeench's Labyrinth. So it can be scaled to the powers of Realspace Slaanesh. The Dark Prince's Realm is divided into six domains, all arranged into cocentric circles around Slaanesh's Palace of Pleasure. Each drives those who wander into it further into temptation and madness. Let's talk about them.
The first is the Circle of Avidity. Here there lies a world of boundless wealth, with the skies themselves shining as diamond and mountains of gold and jewelry cascading from waterfalls. The entire land is made of fortune beyond measure, and only the strongest of will can pass it, as if you are tempted by the riches for even an instant, your very consciousness shall become one with it, your entire being crystallized into gold and gems.
Second is the Circle of Gluttony, a world filled with an endless banquet of every culinary wonder there is, and no matter what you hunger and thirst for, you shall find in abundance. Said feast holds taste, scent and appearance so wonderful it's incomparably greater than any other food. Should you fall to your desires and taste a single delicacy, you shall become a bloated fool who's only desire is to eat until the moment of your death.
Third is the Circle of Carnality, a land where your every sexual desire may take form, and every conceivable and inconceivable carnal pleasure can be experienced. The sights of this place will drive anyone made with lust, and upon falling to the temptation your very soul is devoured by Daemonettes.
Fourth is the Circle of Paramountcy, a world where you are adored as supreme by an infinite crowd, and will be granted absolute power, and hailed as perfect. All live for your sake, and nothing is beyond your reach, though in actuality it is an empty, decaying world where you'll remain forever in delusions.
Fifth is the Circle of Vainglory, a world where you are relived of the previous temptations, and can dwell in pure blissful fantasies. Here, everything you ever desired to be, wished you were, or believe to be are reality, and with all your goals achieved, all your dreams and desires fulfilled, you can finally rest in satisfaction, though doing so will claim your soul as you are reminded of all your failures in the final instant.
Finally, Sixth is the Circle of Indolency, a land of heavenly beauty where all is in pure harmony, and the very air fills you with a narcotic-like sense of peace. Here, everyone remains in happiness and love in a world devoid of all suffering and pain. Though, if one savors such a world for the slightest instant, and you shall be mindless and trapped till the last of your days.
For the few legendary souls who traverse past the Circles of Temptation, Slaanesh's palace awaits, where they will soon learn that their arduous and torturous journey was for naught. All that has been offered and witnessed so far is but a fraction of Slaanesh's true self, whose indescribable beauty, the very embodiment of pleasure and desire, instantly destroys all sense in the minds and souls of those who gaze upon it. There are no exceptions, all mortals who come this far are fated to become Slaanesh's mindless servants.
. . . And The Emperor is capable of fighting against a serious Slaanesh and suffer no consequences. More, Slaanesh is but one, and the weakest of the 4 Chaos Gods, and their combined might is incapable of destroying the Emperor's will and soul.