I'm perfectly fine with applying this to live action stuff as cinematographic devices and principles apply to something that has been filmed. As for animation, I don't think this would apply. Just like with comic panels, animation comes across the same issues I had before when it comes to applying this logic to drawings. Everything regarding drawings relies on artistic interpretation and stylization as opposed to anything involving cameras.
Let's look at Total Drama for example as that is a wild example of stylization (plus I've had people compare the art style to Butch Hartman stuff), having the humans be largely polygonal in appearance. The animation used Adobe Flash (now Adobe Animate) and Toon Boom, the latter which was designed for animators. The former doesn't have anything regarding FoV, and I'm saying this as someone who had to use that program in high school. I wouldn't know anything about Toon Boom, however. The show itself is heavily stylized and perspective goofs go as far back as the very second episode of the show:
In this case, there are two measuring sticks available: the cliff (which is officially stated to be 1000 feet tall) and Lindsay (who is officially measured at 5'9" from the top of her character model down in a TV special). Keep in mind that the tiny offset of the locations of both the bottom of the cliff and the bottom of Lindsay's feet along the Z-axis as depicted in the scene is apparently the animators' idea of being right next to something, as seen here:
As shown in the scene of Owen's splash using a 1366x768 px screenshot, Lindsay is roughly 25 pixels tall, yet the cliff is 611 pixels tall. Using the cliff's size, Lindsay would be considered this tall:
25/611*1000=40.91653028 feet tall
Whereas if I used Lindsay's height, I would get this height for the cliff:
611/25*5.75=140.53 feet tall
This would in effect throw any concept of using cinematographic FoVs for angular sizing right out the window as no camera can account for the discrepancy that the animators put out.
Also, if I were to find this... creature, photograph it, and then sell the photos online, I wouldn't be on this forum today because of all the money I'd make: