Of course, although I don't think the bar is low to human standards.
There are many cases where fiction exaggerates "mastery" which can confuse some people. Having "mastery" means having "comprehensive knowledge or skill in a subject or accomplishment". If a character knows how to aim a gun accurately, handle a gun properly, and shoot it effectively, like Teardrop demonstrated she can, then they pretty much know everything there is to know about using that weapon. That means the character has comprehensive skill in the subject of using a gun to human standards, so they have mastery of it. The character doesn't need to be doing midair 360° spin pistol snipes from kilometers away for their skill to count as mastery, since that would require uncanny accuracy beyond realistic skill, so it would be a deeper extent of mastery than the baseline as a result of a character's supernatural capabilities allowing them to have skill that's impractical in real life.
For weapons like sticks or knives, the bar is higher because it doesn't take an expert to be able to reliably whack or poke something in combat with an item. However, simple feats like Agent 47 from Hitman being able to reliably kill targets by throwing a sharp weapon like a knife at them from a few meters away counts as weapon mastery, since that's not easy to accomplish without impressive skill.