Powerpuff Girls Z The Big O.
Just going to expand on this, because past the stupid bullshit it's a serious suggestion.
The Big O is an anime centered around a character named Roger, a rich private investigator, who, with the help of his robot assistant
Dorothy, uses his giant mecha Big O to solve various mysteries and problems throughout the city. The main draw of the show that'll keep you hooked is this tidbit:
No one knows whats outside the dome covering the aforementioned city, and no one has memories of anything beyond the last 40 years, apparently.
It shares a lot in common with
Batman The Animated Series, which makes sense given of most of The Big O's staff had just come off animating that show.
I've also seen it compared to
James Bond, which I'll refute, it's more like
City Hunter, but instead of the Dorothy beating Roger with a hammer every time he does something perverted to a client or other character, you know classic anime trope, she reminds him, with the same deadpan voice, at every oppertunity, honestly even when he's not being perverted, that she's a robot and that her cold lifeless body despite her various attempts to do so, will seemingly, and tortuously, never understand why Roger acts the way he does. That last bit being something at times he himself can't even answer.
It's 25 Episodes, and despite being on streaming services, the license holders barely if at all use YouTube's copyright bots to full effect. It's not a particularly mainstream series anymore I guess despite Steve Blum dubbing the main character, and it being on [adult swim] back in the day.