As long as Bruno is trying to kill him intially he likely would take it, if Kira somehow tips him off that he makes bombs via his hands, he's getting the secco treatment as well.
If Bruno isnt trying to kill but Kira on the other hand is, I'm sure he can lull Bruno into his melee range and land a blow or trick Bruno into touching a bomb of his when he's unaware like he did Harvest or with the door knob (or panties).
If Bruno wants to finish off Kira right away then he can likely just finish him off via blitzing before Kira can even get a chance to bomb him or anything and decap.
Bruno has the advantage with hindering his opponents, capable of instakilling if he lands a blow on the right place, more experience and skill, SHA wouldnt track him thus it aint a factor unless Kira can give it specific commands (he may be capable of doing so if his final use of it is any indication), has the AP advantage by a fair amount and a huge speed benifit over Kira due to scaling off Chariot and thus SP (who blitzes Kira when half dead), mobility advantage, stealth and can hide, normally fatal wounds wont kill him (heavy bodily destruction is a must, impaling, slit throats, ruptured organs, etc arent gonna stop him), has double the stand range of killer queen too, longer with zipper punch.
While Kira has SHA (would ohko Bruno plus his stand with no questions asked if hot enough and SF aint stopping it physicaly if SP cant, zippers may complicate it though), can instakill if he gets Bruno to make contact with a bomb via transfer, instakills if Bruno is touched directly by him or his stand and a much better starting mindset when cornered (trying to erase the opponent via his bomb).
Bruno definitely has more advantages but Kira's advantages are insta wins. I'd give it to Bruno though speed unequal while equal could go either way as basically at that point its who touches the other first.