Is not dura negation, is more attacking the insides of someone
Mana zone allows the user to spawn spells in an area, including persons, other people spells, behind you, around you, etc
Normally, this technique have to surpass mana skin of other people or even mana zone, also the fact that other people should be able to tell that someone is gonna use mana zone on you, so is extremely difficult to land a mana zone inside someone for all of this reasons, as everyone in BC is gonna sense the mana inside them suddenly changing from said use of Mana Zone, but against someone without Magic (but I can buy that some quirks could let him deduce him in other way, because Danger sense is literally the same for example), Yuno just use mana zone inside someone and is over
And the range is hundred of metters, the recent Yuno would have Kilometers though, but not important here, also, the range could probably be kilometers thanks to the movie, but that would need a CTR and pixel scaling and I don't know how to do it so I just wait
Edit: And Yuno would normally not blow up people but after seeing this monster with no magic? No different from how he literally blow up devils