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Not everyone in D&D can naturally bypass magic defenses. Like random peasant #46672 or that level 2 fighter who guards a small village won't have anything to get past a werewolf. But higher level people (like say Hercules) will possess heavy duty weapons that can punch through the abstractness of the enemy or monsters with similar resistances can bypass stuff of equal or lower level (i.e. a Pitfiend could bite a Vampire and do damage but the reverse wouldn't be true).