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The marks, to me, is showing the curse has been applied and is spreading as it had been explained to us multiple times that it acts like a poison and even the first few chapters give off the impression the curse still act pretty similar to how a poison works.the marks don't spread in the blood flow , but in the victim skin, and if you say something like "that doesn't change the fact that Mori can still stop the blood flow of the skin" its absolutely wrong
the curse are the marks, they are magical, not physical, Mori can't stop it with acupunture