The likes of wakanda, Gotham city and more are very different settings to the everyday real world cities or countries we see. Avengers Tower has an active AI running it. They all have features which can realistically differentiate them from one another.What relevance does Wakanda having guards, Gotham having heroes/villains and Avengers Tower having Jarvis hold? Allowing interference from different characters in a vs match makes the match unusable, and hence does not serve any purpose. The wiki is for indexing characters, not every location from fiction just because they have minute differences like having guards, heroes, etc.
Yes, if a skyscraper or city visually massively resembles and is clearly no different from a real life equivalent (such as Marvels New York City for example) we aren't going to have a new York City profile for every version of the city in fiction, because they would all be the same with minute differences. But we can make profiles for the buildings or such that differentiate them, as they would be different enough from everything else to be valid enough for a profile.