First thing, the Spot's lifting strength is wrong, you get Class 1 by snapping necks with a single hand, using both arms makes the work much more easier and is
athlete level.
Edit: I looked at the wrong calc for that, but still, just snapping necks with two arms and technique
isn't considered enough for Class 1.
Also, do
these two
scans come from a reliable source? They are on Mysterio's profile, but they might not qualify for what we consider valid.
Second, do they know each other?
Without knowing the answer to the first question, for now I think Mysterio has more chances to win this.
One day of preparation means he likely doesn't have the time to build any special robot (unless we assume he has all of them available) but it would be easy for him to research who The Spot is, he should be rather famous overall through public domain.
Mysterio can pack himself up (and maybe even set traps and shit on the battlefield) to **** around with Spot's perception, senses and even just plain smoke to block his sight while he senses him with his sonar device.
Then the Spot can be incapacitated with guns, poisons, tranquilizers and electricity.
Spot can still move around and expect something if he knows Mysterio, as well as block him with multiple limbs, but gases and smoke are AoE and knowing that, Mysterio isn't just going to go there unprepared, showing his true self or not casting immediately something that can hide himself and decept the Spot.
Mysterio's electric cape could also fend off the Spot trying to grab him from afar.
I'm prone to vote Mysterio even if the Spot knows who he is.