Ok, so, Marvel's biggest advantages are her ability to absorb energy and her lifting strength. Everywhere else...she falls very short. Heck, even those advantags aren't that great. Her energy absorption is not a be-all, end-all due to the fact that we don't know how much and how fast she can absorb energy. Sure, she drained a ship but I don't think that compares to Goku's ki reserves or the amount of power behind his energy attacks. Plus, this is android saga Goku, and he'd have experience from dealing with 19's abilities. Furthermore, unlike 19, CM can't increase her states via absorbing energy. The lifting strength is somewhat trickier, but Goku does little actual grappling compared to punches and kicks, so he'd quickly suss out that isn't a good idea after any clash when CM ragdolls him. Plus, CM doesn't have the skill level to really force Goku into a grappling.
Goku has a small ap/dura advantage. He is also way, way more experienced in combat with decades of training under multiple teachers, a vaster array of opponents and is utter prodigy in understanding fighting in and of itself. His tenacity and stamina in combat are just more than anything CM has as well, pushing through pain and exhaustion that she has just never demonstrated.
Goku should solidly take this. CM's abilities make her a bit of a pain to deal with in a practical sense but she's painfully straightforward and has nothing that Goku has not seen before. He'll simply rise to the occasion, fight around her advantages and take her down.
