Yes, but he'll counter with Quicksilver if it is activated, that's a fact
Also, there are other things to consider
It is a close attack ? Because with range, Dante even being slower can block it with Royaguard or evade, or even activate Quicksilver, just like a human can evade a car even being slower, only needing a moment to react. If she needs to get closer to use, it will be a chance for Dante block or evade aswell, because her movement speed is MHS+, not Sub Rel +, so Dante can react easily to her approach
And he have Ice Manip to restrain her movements, Agni and Rudra to maintain a distance and for ranged Attacks, and Flight with Nevan DT and being capable of atack with Lightning and his pistols
Can her attck him on the air ?
And with Doppelganger, one Dante can use Ice Manip and the other can Flight and attack with Lightning, mixing these abilities
And Dante have Enhanced Senses, he can activate Quicksilver before or even evade Quicksword just like I said above, depending on how it works, but at close range or long range, Dante can avoid