Alright,
Berserker's hax are the deciding factor here. Not only would any of Orphelia's hax just... not work against her, but even the Meta-Luck would be countered by Berserker's possibly High-Godly to potentially True-Godly Regenerationn negation, as well the Reactive Evolution to sufficiently counter her opponent's abilities. I.E: Eventually develop resistance-bypassing Concept Destruction. RE also eventually leads to reality giving Orphelia the middle finger, since Berserker will just become stronger, and "better" than Orphelia at a faster rate. With what I'll mention next, Berserker doesn't even need to worry about Orphelia's RE.
Additionally, even Probability Manipulation counters Type 8 Immortality and the High Multiversal durability, as just like the profile suggests, it manipulates the chances of literally anything happening and requires more than just a resistance to probability hax (which Orphelia doesn't have a sufficient degree of, as this worked on both BB and Kiara, who have Type 5 Acausality) - So, this can convert to conceptual destruction on whatever the sufficient level is. For Berserker in this situation, that'd be type 2 or 1.
Passive Power Nullification also helps.
I vote for Berserker.