So BSM Naruto and EMS+Senjutsu Sasuke vs SM Hashirama. Honestly, this is probably a hot take, but I think BSM Naruto stands a really good chance at pulling it off. Add in another person relative to him (at least according to the website) and I don't think Hashirama stands much of a chance. A lot of Hashirama's feats are a lot less impressive when you really think about it. Like in base catching a bijuudama, since that was a really small bijuudama that was insta launched, and it still destroyed his wood dragon and wood golem when it exploded. And his only real SM feats are using the shinsu senju, restraining the juubi, and fighting Edo Madara with buffs. These are great feats, but the shinsu senju's arms were partially countered by rapid fire susanoo bijuudamas, which Naruto and Sasuke could replicate but far stronger because BSM Naruto>>Kurama and Sasuke (in this form) ~ EMS Madara. And the shinsu senju afterwards only destroyed part of the PS, while Sasuke's armor would be more durable due to the senjutsu buff and less or no arms would hit it. As for restraining the juubi, the site doesn't consider that AP, and with senjutsu sensing, Naruto and Sasuke could avoid that most likely. And while Edo Madara is very strong, he's not as strong as BSM Naruto and EMS+SM Sasuke together.
As for how they'd actually win, they have a speed advantage, so they can use that to overwhelm in cqc (not sure how Sasuke would have Jugo's energy in human form, but even just EMS Sasuke along with BSM Naruto would heavily pressure Hashirama), if Hashirama tries supressing bijuu chakra with like the wood golem or dragon Naruto could destroy it easily with a bijuudama or slashing it to pieces. In fact there's not much in general Hashirama could do about a supercharged bijuudama maybe amped with amaterasu or something, that has 6-B or higher AP compared to Hashirama's compartively meager Low 6-B durability. And if they use majestic attire, it's gg for Hashirama. So the team probably takes it low-mid diff.
