Thanks for the answer. But isn't this directly contradicted in Giorno's fight with Bruno? GE implements Bruno with a certain amount of life, and all it does is make his senses go out of control. This is also the mentioned effect on human beings on GE's profile.
But it varies, it's pulled off by essentially overloading something with so much life energy that they exhaust their life span.
The effect varies depending on how much he gives and how long the target in question would normally live for.
Something like a bug, takes not even a fraction of a fraction of a second of contact. But something like a tree with a 50-60y life expectancy would take at least a few seconds of direct contact.
So yes, it works on humans, and life In general, but to varying degrees. It also needs direct contact for GE and isn't a lead.