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I am pretty knowledgeable about Marvel Comics, except for the cosmology. So how does it work? Are there an infinite number of planes of existence in 616, or in the Multiverse as a whole? Or both? Is the World Tree a structure that exists across the Multiverse, or is a Multiversal structure that exists entirely in 616 (with different versions in other universes)? Are spaces like the Cancerverse part of 616 specifically, or are they another Universe in the Marvel Multiverse? If they are all within 616, would that make destroying the 616 Universe a Multiversal feat.