So essence in this case includes things like the soul and mind, rather than just fully-realized forms?
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"Dark Samus has temporarily become a being of pure yet unstable Phazon energy. She can generate a shield that is invulnerable to all attacks, save one -- blasts of Phazon energy itself. Use your Charge Beam to collect Phazon energy that she expels, then fire it back at her. Direct hits will overload and disrupt her essence."
And the temporary scan of Metroid Prime states something similar about fighting her essence:
"Morphology: Metroid Prime
The core essence of Metroid Prime."